As you can see at the end of my benchmark post, the 3 acceptable ways (performance wise) to do a bulk insert in Psycopg2 are 

• execute_values() – view post
• execute_mogrify() 
• copy_from() – view post

This post provides an end-to-end working code for the execute_values() option.

Step 1: Specify the Connection Parameters

import pandas as pd
import psycopg2.extras as extras
# Here you want to change your database, username & password according to your own values
param_dic = {
    "host"      : "localhost",
    "database"  : "globaldata",
    "user"      : "myuser",
    "password"  : "Passw0rd"
}

Step 2: Helper Functions

def connect(params_dic):
    """ Connect to the PostgreSQL database server """
    conn = None
    try:
        # connect to the PostgreSQL server
        print('Connecting to the PostgreSQL database...')
        conn = psycopg2.connect(**params_dic)
    except (Exception, psycopg2.DatabaseError) as error:
        print(error)
        sys.exit(1)
    print("Connection successful")
    return conn

def execute_values(conn, df, table):
    """
    Using psycopg2.extras.execute_values() to insert the dataframe
    """
    # Create a list of tupples from the dataframe values
    tuples = [tuple(x) for x in df.to_numpy()]
    # Comma-separated dataframe columns
    cols = ','.join(list(df.columns))
    # SQL quert to execute
    query  = "INSERT INTO %s(%s) VALUES %%s" % (table, cols)
    cursor = conn.cursor()
    try:
        extras.execute_values(cursor, query, tuples)
        conn.commit()
    except (Exception, psycopg2.DatabaseError) as error:
        print("Error: %s" % error)
        conn.rollback()
        cursor.close()
        return 1
    print("execute_values() done")
    cursor.close()

Step 3: Main Code

# Read the csv file
    # Read your dataframe
    df = read_dataframe(csv_file)

    # Connect to the database
    conn = connect(param_dic)

    # Run the execute_many strategy
    execute_values(conn, df, 'MonthlyTemp')

    # Close the connection
    conn.close()

For a fully functioning tutorial on how to replicate this, please refer to my Jupyter notebook  and Python script on GitHub.